---
description: Side-by-side comparison of Proofpoint Email Protection vs Microsoft Defender for Office 365. Learn more about each of the product's price, features, and see the most comprehensive reviews for UK business users.
image: https://gdm-localsites-assets-gfprod.imgix.net/images/capterra/og_logo-e5a8c001ed0bd1bb922639230fcea71a.png?auto=format%2Cenhance%2Ccompress
title: Proofpoint Email Protection vs Microsoft Defender for Office 365 Comparison - Capterra UK 2026
---

Breadcrumb: [Home](/) > [Computer Security Software](/directory/10005/computer-security/software) > [Proofpoint Email Protection \<span\>vs\</span\> Microsoft Defender for Office 365](https://www.capterra.co.uk/compare/175873/219685/proofpoint-email-protection/vs/microsoft-defender-for-office-365)

# Compare Proofpoint Email Protection vs Microsoft Defender for Office 365

Canonical: https://www.capterra.co.uk/compare/175873/219685/proofpoint-email-protection/vs/microsoft-defender-for-office-365

> Detailed comparison between Proofpoint Email Protection and Microsoft Defender for Office 365. Check ratings, reviews, pricing, and features to make the best decision for your business.

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## At a Glance

| Metric | Proofpoint Email Protection | Microsoft Defender for Office 365 |
| **Overall rating** | 4.2/5 | 4.6/5 |
| **Total Reviews** | 45 | 235 |
| **Starting Price** | - | - |
| **Free Trial** | Yes | No |
| **Free Version** | No | - |
| **Deployment** | Cloud, SaaS, Web-based, Windows (Desktop) | Cloud, SaaS, Web-based |
| **Support** | Email/Help Desk, FAQs/Forum, Phone Support, 24/7 (Live rep), Chat | - |
| **Training** | Live Online, Webinars | Live Online, Webinars, Documentation, Videos |

## Best for

### Proofpoint Email Protection

Online email protection tool that enables businesses of all sizes to filter, detect \&amp; block any inbound or outbound threats \&amp; imposter attacks through internal mail defense.

### Microsoft Defender for Office 365

DevOps and Security Operations (SecOps) teams&#10;Security engineering teams&#10;IT teams&#10;CISOs and CTOs&#10;Red, Blue, and Purple Teams&#10;CSIRT \&amp; forensic team&#10;Microsoft 365 administrators

## Key features

### Proofpoint Email Protection

- API
- Alerts/Escalation
- Anti Spam
- Application Security
- Email Filtering
- Email Monitoring
- Encryption
- Event Logs
- Monitoring
- Phishing Protection
- Policy Management
- Real-time Alerts
- Reporting/Analytics
- Spam Analysis
- Spam Blocker
- Spam Quarantine
- Threat Protection
- Threat Response

### Microsoft Defender for Office 365

- Alerts/Escalation
- Anti Spam
- Email Filtering
- Email Routing
- Filtering
- Phishing Protection
- Policy Management
- Reporting/Analytics
- Spam Blocker
- Spam Quarantine
- Threat Protection
- Threat Response

## Links

- [View Proofpoint Email Protection Profile](https://www.capterra.co.uk/software/175873/proofpoint-email-protection)
- [View Microsoft Defender for Office 365 Profile](https://www.capterra.co.uk/software/219685/microsoft-defender-for-office-365)
- [View Original Comparison](https://www.capterra.co.uk/compare/175873/219685/proofpoint-email-protection/vs/microsoft-defender-for-office-365)

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